A conversion of Cholest-4-en-3-one into Cholest-5-en-one
نویسندگان
چکیده
منابع مشابه
Cholest-5-en-7-one
In the deca-hydro-phenanthrenone ring system of the title compound, C(27)H(44)O, the two cyclo-hexane rings adopt chair conformations, whereas the cyclo-hexene ring adopts an envelope conformation. The cyclo-pentane ring is twisted. In the crystal structure, mol-ecules are stacked along the a axis, but no significant inter-molecular inter-actions are observed.
متن کاملCholest-5-en-3β-yl N-phenylcarbamate
In the title compound, C(34)H(51)NO(2), the dihedral angle between the planes of the phenyl ring and the carbonyl group is 9.30 (2)°. No significant inter-molecular inter-actions are observed in the crystal structure. The C(5)H(11) fragment is disordered over two positions with site occupancies of 0.611 (6) and 0.389 (6).
متن کاملtrimethylchlorosilane; cholesterol, Cholest-5-en-3b-ol; oxysterols, cholesterol oxidation products; 7-ketocholesterol, cholest-5-en-3b-ol-7-one; cholestanetriol, cholestan-3b,5a,6b-triol; a-epoxycholesterol, cholestan-5a,6a-epoxy-3b-ol; 25-hydroxycholesterol, cholest-5-en-3b,25-diol; 7a-hydroxycholesterol, Cholest-5-en-3b,7a-diol; 7b- hydroxycholesterol, cholest-5-en-3b,7b-diol; b-epoxycholesterol, cholestan-5b,6b-epoxy-3b-ol; 27-hydroxycholesterol, 25R-cholest-5-en-
Abbreviations : HMDS, 1,1,1,3,3,3-hexamethyldisilazane; TMCS, trimethylchlorosilane; cholesterol, Cholest-5-en-3b-ol; oxysterols, cholesterol oxidation products; 7-ketocholesterol, cholest-5-en-3b-ol-7-one; cholestanetriol, cholestan-3b,5a,6b-triol; a-epoxycholesterol, cholestan-5a,6a-epoxy-3b-ol; 25-hydroxycholesterol, cholest-5-en-3b,25-diol; 7a-hydroxycholesterol, Cholest-5-en-3b,7a-diol; 7b...
متن کاملIdentification and Characterization of TRO19622 (Cholest-4-en-3- One, Oxime), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
Trophos, Parc Scientifique de Luminy case 931, 13288 Marseille cedex 9, France (T.B., B.B., M.M., C.D., P.G., P.D., E.S., D.M., M.D., R.M.P.) ; Washington University School of Medicine, Saint Louis, MO, USA (N.P.A., A.S.E., D.F.C.); U773 Inserm, Centre de Recherche Biologique Bichat Beaujeon (CRB3), Université Paris 7, Faculté de Médecine Bichat, 16 rue Henri Huchard, BP 416, 75018 Paris, Franc...
متن کاملIdentification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive death of cortical and spinal motor neurons, for which there is no effective treatment. Using a cell-based assay for compounds capable of preventing motor neuron cell death in vitro, a collection of approximately 40,000 low-molecular-weight compounds was screened to identify potential small-mol...
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ژورنال
عنوان ژورنال: Australian Journal of Chemistry
سال: 1953
ISSN: 0004-9425
DOI: 10.1071/ch9530445